Our in vitro hepatotoxicity assays are implemented using Transporter Certified™ hepatocytes in sandwich culture. Our methodology ensures that hepatic uptake and efflux transporters are functioning in the model, and therefore intracellular concentrations (ICC) reflect physiologic conditions in vivo.
Our hepatotoxicity evaluation programs include:
- Cytotoxicity Assessment
- Mechanisms of Toxicity
- Cholestatic Hepatotoxicity Evaluation