CYP450 Induction Kit
The AccuLiver CYP450 Induction Kit is used to assess the CYP450 induction potential of a test article. The kit includes materials which enable establishment of a model, that, when combined with Transporter Certified™ hepatocytes, has demonstrated better in vitro-in vivo correlation than conventional, transporter-deficient models. Transporter Certified hepatocytes, when cultured in the conditions described in the manual, express physiologically-relevant transporter function resulting in in vivo-relevant intracellular concentrations making the model more appropriate to predict induction potential.
The AccuLiver CYP450 Induction Kit enables our clients to duplicate the experimental conditions in-house that we at Qualyst have developed and routinely use in our laboratory.
The AccuLiver CYP450 Induction kit contains the following items needed for the induction assay:
Collagen Coated 24-well plate (2)
QualGro™ Seeding Medium (50 mL)
QualGro™ Overlay Medium (30 mL)
QualGro™ Induction Medium (100 mL), formulated to give a suitable dynamic range for CYP450 induction
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